The Negative Pressure Ambulance consists of an ambulance body, a head cover, an air pipe, and an inner negative pressure purification system. It is an ambulance with special enhancements to help safely treat and transport patients with infectious diseases. Its main point is the negative pressure purification system, which is able to form a negative pressure zone inside the van and the inner filtering air will be discharged through air pipe. In that case, the special ambulance ensures minimizing possibility of communicable diseases spread during infected patients transport.